New strategies to combat mutlidrug resistant bacteria with nanoengineered peptide polymers

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Many Gram negative microbes have acquire antibiotic resistance and the design of new antimicrobials targeting these bacteria is lacking. Research teams from Australia have developed a new class of antimicrobial agents using ring-opening polymerization (ROP) process with alpha amino-acids lysine and valine to produce star-shaped peptide polymer nanoparticles.